Alan goes up against an ex who got away and he's not completely over in a case against Big Tobacco, and Denny is too busy to help because he's worried about his impotence problem.

Jerry and Katie lock horns with Melvin Palmer over the rape of their client's daughter. Alan locks horns with the pharmaceutical company over misleading information supplied to Denny, who collapses on the floor. Carl locks horns with the government over Shirley's granddaughter for underage voting in the Massachusetts primary. Written by Moviedude1

Denny faces concealed weapons charges after he shoots a mugger, and Alan confronts his own sexism as he represents a sexual surrogate in a child custody case.

Being noted as a great lawyer attracts the attention of a former girlfriend as she asks Alan to defend her husband in a murder trial, even though he still has feelings for her which compounds the case in a conflict of interest.

Denny's attempts to stack the deck in his favor over a wager with Alan jeopardizes both their positions in the firm, their ability to practice law, and, most importantly, his valued friendship with Alan. Shirley agrees to represent a man whose brother died in the Armed Forces, yet compensation for the death lies at the hand of the doctor attending him, rather than the enemy. And Jerry confronts his nephew and the possibility that his nephew's new girlfriend may also be his half-sister. Written by Moviedude1

Alan and Denny take a vacation to a dude ranch, where Alan's reserved demeanor and Denny's footloose attitude seem to cause nothing but trouble. Jerry's wishes to become a partner are jeopardized when he shows up in a Halloween costume a week before the 31st, while Shirley answers a page for Alan from Catherine Piper, who's in jail and ordered to stand trial for the attempted murder of a local physician. Written by Moviedude1

Alan asks Denny to assist him in a case where their client is being sued by the Department of Agriculture in order to stop her from testing all her cattle for Mad Cow Disease, while opposing counsel is former firm employee Denise. Jerry is recommended for partner by Shirley and Carl, while the board does not see eye to eye with them. Written by Moviedude1

Alan and Shirley confront their own misgivings about legalized abortion as they defend a 16-year-old Chinese immigrant who wants one. Meanwhile, Jerry faces assault charges after punching out a man in a coffee shop who ridiculed him.

Denny and Carl go to Virginia to defend a corrections officer who shot and killed an inmate during his botched execution, and Alan and Shirley defend one of Alan's old classmates who says she was fired because she voted for John McCain.

Different topics abound at Shirley's house for Thanksgiving when then gang assembles for what was supposed to be a quiet intimate dinner for two between her and Carl.

As Denny finds out he's in the early stages of Alzheimer's, he also learns that there may be a drug not available to him that may prolong his life. Katie and Jerry agree to help a client get back into Harvard after admitting to academic doping. Catherine Piper returns, out of sheer boredom, to be a pain in Carl's side while Shirley is away. Written by Moviedude1

In the 100th episode of the series, on the verge of bankruptcy, the firm is bought by a large Chinese corporation. Horrified by this, Shirley goes to court, trying to get an injunction against the deal. While getting ready to argue their case in front of the supreme court, Denny makes a surprising proposal to Allen. Written by aremid63

In the series finale, Allen leads Denny's case in front of the supreme court, regarding his right to use an experimental treatment. In a double wedding ceremony, performed by Supreme Court Justice Scalia, Shirley and Carl, and Denny and Allen at long last tie the knot. Finally, The Zhu corporation, who bought the firm, changes its name to Chang, Poole and Schmidt. Written by aremid63